Author's response to reviews Title: Tubular reabsorption and local production govern urine hepcidin-25 excretion Authors:
نویسندگان
چکیده
format. All authors have approved the final version of the article. There are no conflicts of interest to declare. We thank the reviewers for their constructive comments and hope that you find our revised manuscript suitable for publication in BMC Nephrology. Yours sincerely, on behalf of the co-authors,
منابع مشابه
Tubular reabsorption and local production of urine hepcidin-25
BACKGROUND Hepcidin is a central regulator of iron metabolism. Serum hepcidin levels are increased in patients with renal insufficiency, which may contribute to anemia. Urine hepcidin was found to be increased in some patients after cardiac surgery, and these patients were less likely to develop acute kidney injury. It has been suggested that urine hepcidin may protect by attenuating heme-media...
متن کاملCombination Therapy with Losartan and α-Tocopherol in Acute Ureteral Obstruction-Induced Renal Excretory Dysfunction and Acidification Defect
Background: Previous study by the authors showed that a-tocopherol prevents oxidative stress but would not improve depressed excretory variables in post-obstructed kidney (POK) after release of 24-h unilateral ureteral obstruction (UUO). This study is a supplementary investigation on the effects of a-tocopherol combined with an antagonist of angiotensin-II type-1 (AT1) receptor on renal dysfunc...
متن کاملHepcidin assays: ironing out some details.
I ron is the fourth most common element in the earth’s crust and the most abundant transition metal in the human body. It is an essential element required for growth and survival. Maintaining the correct iron balance is crucial for health. All living organisms evolved sophisticated mechanisms to maintain appropriate iron levels in their cells and within their body. It was shown recently that th...
متن کاملAuthor's response to reviews Title: Physicochemical analysis of blood and urine in the course of acute kidney injury in critically ill patients: a prospective, observational study Authors:
Title: Physicochemical analysis of blood and urine in the course of acute kidney injury in critically ill patients: a prospective, observational study
متن کاملRenal effects of a urodilatin infusion in patients with liver cirrhosis, with and without ascites.
This study reports the effects of a short-term (60 min) low-dose (20 ng x kg(-1) x min(-1)) infusion of synthetic urodilatin (URO) in patients with liver cirrhosis. URO is a natriuretic peptide. A total of 15 cirrhotic patients with ascites and nine without ascites participated in a randomized, double-blind, placebo-controlled study in a crossover design. Renal hemodynamics were estimated by a ...
متن کامل